It's always a balance of tradeoffs and benefit. That might work, but there are already alternatives. If possible, change the design so that the anticipated load is acting on the x and y axis of the print. If that's not possible, another common tactic is to do something like partial print > insert metal rod in printed channel along y axis > resume print.

Resin would be very interesting. The tube design seals them everywhere below the top layer. And the two ends of the tube tops are always at the same Z.

You could technically inject anything liquid enough into the tubes. Grout, resin, glue, silicone.